Well-known as Actinomycin D in the pharmaceutical world, Dactinomycin is an antineoplastic chemotherapy drug used for the treatment of Wilms' tumor, ovarian cancer, metastatic testicular tumors, Gestational trophoblastic neoplasm, Ewing's sarcoma, childhood Rhabdomyosarcoma, soft tissues sarcoma, and Osteosarcoma. It has been classified as an antitumor antibiotic that aims at destroying the DNA of the cancer cells so that it cannot divide, and further growth is stopped.
Dactinomycin Uses and Dosage Firstly, it is given in combination with other anti-cancer drugs like Vincristine, Actinomycin D, Cyclophosphamide, and Ifosfamide. Dactinomycin injection is given intravenously as a drip into the bloodstream. A small tube or a cannula is placed into one of the veins that help connect the drip. Since Dactinomycin 0.5 mg is a vesicant drug, it can severely damage the tissues that come in direct contact with it. That is why it is mandatory to get it from a trained professional at all times. Usually, it takes around 10-15 minutes for infusion. This drug therapy is conducted in cycles, and the dosage varies depending on the type of cancer, your health condition, body weight, medical history, etc. The cycles last from 8 weeks to 112 weeks, based on the type of condition that is being treated and the response from the body. It is typically administered once every 3 weeks for most conditions. Precautionary Measures While receiving Dactinomycin injection, go through the following precautionary measures to stay safe:
Side Effects of Dactinomycin 0.5mg
Dactinomycin's side effects are entirely predictable and manageable. Sometimes they are dependent on the other treatments that you are receiving currently like radiation therapy. They easily go away once the therapy is stopped. Note that early treatment will definitely help you to cope with the side effects better. If you have a very high fever with a body temperature of 37.5 degrees C or more, contact your healthcare professional immediately. Commonly Asked Questions: 1. What are the uses of Actinomycin? The actinomycin uses are as follows:
Yes, Actinomycin D is a chemotherapy medication. 3. Is Dactinomycin an antibiotic? Dactinomycin specifically is an intravenously administered, antineoplastic antibiotic drug, used for the treatment of solid tumors in children and choriocarcinoma in adult women. 4. How do you take Actinomycin D? Actinomycin D is taken by injection into a vein. 5. How does actinomycin D work? Actinomycin D is a polypeptide antibiotic isolated from the genus Streptomyces. This drug intercalates into DNA, preventing the RNA polymerase's progression. It is widely considered as a transcription inhibitor. Conclusion Before starting therapy, your doctor will conduct a thorough medical checkup to determine whether your condition is suitable for it. The medicine also alters your WBC count. Routine checkups will be conducted to monitor your disease progression and health conditions. The cost of Dactinomycin 0.5 mg injection is around $1234. The overall survival rate in patients who have received this drug is 100% (disaster-free success rate). Read:- About Eribulin Mesylate
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9/16/2022 12:02:12 am
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AuthorMy Name is Amit Sharma I am a pharmacist, I am having 25+ years of experience in Pharma medications. ArchivesCategories
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