Medication for the treatment for the types of psoriasis and psoriatic arthritis is known by the name Apremilast, mostly sold under the name of otezla. Certain types of psoriasis plague are commonly caused due to the downregulation of immune activity within the skin. The changes in the skin result in epidermal thickening, redness, and itchiness, and scaly plaques.
Development History: The CADTH Canadian Drug Expert Committee (CDEC), in July 2015 recommended that apremilast not be listed for the treatment of adult patients with moderate-to-severe. The main reasons for the recommendation included the lack of comparative evidence with other treatments and inadequate evidence to evaluate the use of apremilast in the patient. Approval history: 21 March 2014, the US Food and Drug Administration (FDA) approved apremilast to treat Psoriatic Arthritis, moderate to severe plaque psoriasis, oral ulcers. It is an oral inhibitor of PDE4 (phosphodiesterase 4). FDA approval was based on safety, double-blind Phase study evaluates apremilast on 207 adult patients with active oral ulcers. The early-stage or first recommendation was at the April meeting, and again was a request for reconsideration that was considered at the July 2015 meeting. Dosage and usage: Approximately 7 million people in the United States get effects with arthritic inflammation, psoriatic arthritis. Psoriatic, a chronic disease, acts on skin with thick patches, scaly skin results in excessive growth of skin cells. As, now apremilast work on different skin and on different cells the dosage is also prescribes in apremilast 10mg/apremilast 20 mg/apremilast 30mg. Mostly, the combination of different users is also advised by the doctor as:
Now the question arises how to take apremilast tablets? It is advisable to take it according to the doctor's prescription. They can be taken with or without food- morning and evening orally through the mouth. It is recommended to take tablets without crushing, splitting, or chewing the tablets. Price: Apremilast comes in different trade brands. The apremilast price of the brand name Aprezo is approximately Rs. 295 (10 tablets). Note:- This is a prescription medicine, while buying online and offline keep a doctor prescription copy handy.
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AuthorMy Name is Amit Sharma I am a pharmacist, I am having 25+ years of experience in Pharma medications. ArchivesCategories
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